In “Secret Wars” (2015), the Marvel multiverse is being destroyed by the multiversal entities known as the Beyonders. Only two remaining universes remain: the main Marvel universe and the Ultimate universe. In the Beyond, Doctor Doom meets with the Beyonders in order to save the remaining universes. Originlly, Molecule Man was designed by the Beyonders as a bomb that would destroy the multiverse. Using Molecule Men as bombs, Doctor Doom and Doctor Strange killed the Beyonders and stole their power.

During the incursions between Earth-616 and Earth-1610, Mister Fantastic built the Future Foundation Life Rafts to transport the survivors to the incursion points. Suffering a hull breach, they nevertheless survived and were transported to Battleworld, created by Doctor Doom. On Battleworld, Doctor Doom was worshipped as God on a world of controlled chaos. There, the Life Raft and the Cabal opposed Doom’s reign. In the end, Doom was defeated and Molecule Man destroyed Battleworld, rebooting the mainstream Marvel universe. In the end, the Ultimate universe was no more.

In ‘Secret Wars’ (2015) #6, the Maker’s and Reed Richards plans are set into motion. Miles Morales and Spider-Man go off to the White Room to find Doom’s source of power. There, in front of Molecule Man’s statue, they find Valeria, Doctor Doom’s daughter on Battleworld but who is actually Reed Richards’ daughter. After a brief discussion with her, the two Spider-Men enter the white room. Inside, they find Molecule Man there who asks them if they brought him something to eat. Surprisingly, Miles Morales takes out a three week-old hamburger from his pocket and gives it to Molecule Man.

Fully fed, Spider-Man asks Molecule Man about Doctor Doom’s power source. Molecule Man tells them they are looking at him. In ‘Secret Wars’ (2016) #9, Miles Morales has a flashback to that moment. In the white room, Molecule Man thanks him for the burger. It is implied that Molecule Man saved Miles Morales and his family in the new mainstream Marvel universe. In the present, the two Spider-Men are on a rooftop and after Peter checks if Miles has done his homework, the two Spider-Men swing into adventure to go beat up on bad guys.

In ‘Venom’ (2021) #200, the Ultimate universe resurfaces. Now, Eddie Brock has become the new King in Black and is testing his super powers. After testing his omniscience, he notes the only one escaping his power is the Maker, Reed Richards’ evil counterpart from the Ultimate universe. Having obtained an artificial symbiote from the Ultimate universe, the Maker used Venom‘s symbiote to augment and heal his psyche.

Able to travel between dimensions, the Maker returned to the Ultimate universe, which was destroyed. Then, Eddie uses his super powers to meet simultaneously the Avengers, Quiet Council of Krakoa, the Guardians of the Galaxy, Silver Surfer and other groups to warn them tat the Maker will likely return to conquer Earth-616. In fact, this task has been commissioned him by the Interdimensional Council of Reeds. In all likelihood, it is possible the Ultimate universe was rebooted after “Secret Wars.”